Righty Walker Buehler will be on the bump for the Padres, marking a rare occasion in which the left-handed-hitting Ortiz is not starting against a right-handed hurler. Yohandy Morales will play first base and will bat fifth for the Nationals.

Ortiz continues to see time in the heart of the batting order against right-handed pitching, but he will head to the bench against another lefty (Justin Wrobleski), as he did Friday against Blake Snell in the series opener. Andres Chaparro will step in for Ortiz at first base. Through his first 31 games in the majors, the 24-year-old Ortiz is slashing .202/.240/.384 with five homers and 11 RBI.