Ryan will lose his spot on the 40-man roster for the second time in three weeks as part of a flurry of roster moves by Pittsburgh on Monday. The 29-year-old appeared in two games during this stint in the majors, allowing three runs across 3.2 innings. He has a 5.66 ERA in 20.2 innings for Pittsburgh this season.

Ryan was designated for assignment by Pittsburgh at the end of July and reported to Triple-A after failing to draw interest on waivers. However, he'll get another crack at big-league action following the placement of Marco Gonzales (forearm) on the 60-day injured list. Ryan has made 13 relief appearances for the Pirates in 2024, posting a 5.29 ERA and 1.41 WHIP with 16 strikeouts over 17.0 innings.